BioBall® 10e8

Calibrated ready-to-use strains for challenge test inoculation

BioBall is a small water soluble ball containing a precise number of microorganisms. Produced to the world’s highest quality standards and ISO Guide 34 accredited, it is ideal for cosmetic industries that perform microbial challenge tests. BioBall is compliant with Pharmacopoeia standards, which require less than 5 passages from the original culture, and is also suitable for ISO 11930 standard.

Rapid & easy preservative efficacy testing

During the development process of all new or modified cosmetic products, cosmetic companies are required to perform challenge tests, or preservative efficacy testing, in order to ensure consumer safety. Extremely accurate and easy-to-use, BioBall is the ideal solution for such operations. It contains a precise number of microorganisms and its high performance has revolutionized quantitative microbiological quality control.

  • Save time in your challenge test process: BioBall is 4 times more rapid than traditional solutions
  • Launch an emergency challenge test at anytime: BioBall requires almost no preparation time
  • 100% inoculation success rate means no retest

Two Solutions adapted to your needs

Each BioBall MultiShot 10E8 has a batch mean between 0.7 and 1.5 x 108 cfu.  When re-hydrated with 1.1 mL of re-hydration fluid it provides 10 x 100μL doses of 107 cfu.  Each 100μL aliquot can be used to inoculate product, resulting in the required final concentration of 105 – 106 cfu/mL product. It is ideal to test antimicrobial preservation efficacy.

Each of the following strains is available separately in packs of 10 vials:

  • Aspergillus brasiliensis
  • Candida albicans
  • Escherichia coli 
  • Pseudomonas aeruginosa
  • Staphylococcus aureus

BioBall Multishot 10E8 Mixed Kits are designed to provide more convenience and flexibility; containing two (2) each of the above strains.

All our solutions demonstrate high quality and considerable advantages:

  • Little or no preparation time: a minimum number of steps
  • Easy to use: BioBall dissolves instantly
  • Greater precisions with a known number of cfu
  • Consistent number of cfu batch to batch
  • Reduces risk of "Failed QC" due to variability of the control

Find more information on our e-catalogue.

Technical Details

Manufacturing BioBall using flow cytometry

BTF, a bioMérieux company, uses patented technology and proprietary techniques to manufacture BioBall products in Australia.

  1. A flow cytometer is used to select and dispense individual cells within a culture, and count them into a single droplet.
  2. Each droplet therefore contains a precise number of viable cells that have been individually selected for maximum recovery rate on non-selective media.
  3. Those droplets are then frozen in liquid nitrogen, dispensed in vials, freeze-dried with a patented technique and sealed under vacuum for maximum shelf life recovery.

bioMerieux's BioBall

Discover a list of available BioBall strains.

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